The study was stopped early around week 64 (V9) due to recruitment issues and data were not pre-specified to be analyzed and reported at week 64 time point as target was with an estimated time point of 432 weeks for primary or secondary end points. The Final Visit value referred to the last value obtained on-treatment.Percentage of patients with transition in albuminuria classes is presented as secondary endpoint. The study was stopped early around week 64 (V9) due to recruitment issues and data were not pre-specified to be analyzed and reported at week 64 time point as target was with an estimated time point of 432 weeks for primary or secondary end points. Least square mean is adjusted mean. The Final Visit value referred to the last value obtained on-treatment.Change from baseline to final visit in creatinine is presented as secondary diabetes-related endpoint. Прямые спортивные видео и текстовые трансляции. Search the world's information, including webpages, images, videos and more. Google has many special features to help you find exactly what you're looking for. Alle Termine stehen schon fest und die Anmeldung ist auch schon möglich. COVID-19 is an emerging, rapidly evolving situation. Wir freuen uns auf ein weiteres Heimrennen in der RMC Austria mit euch!Die RMC Austria freut sich schon auf die neue Saison 2020. The Final Visit value referred to the last value obtained on-treatment.Change from baseline to final visit in total cholesterol, low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol is presented as secondary diabetes-related endpoint. Least square mean is adjusted mean. You have reached the maximum number of saved studies (100).Please remove one or more studies before adding more.The aim of the study is to investigate the longterm impact on cardiovascular morbidity and mortality, relevant efficacy parameters (e.g., glycaemic parameters) and safety (e.g., weight and hypoglycaemia) of treatment with linagliptin in patients with type 2 diabetes at elevated cardiovascular risk receiving usual care, and compare outcome against glimepiride.patient to receive linagliptin or glimepiride placebo over encapsulated tablet Quaque die (QD)patient to receive glimepiride 1-4 mg or linagliptin placebo tablet Quaque die (QD)The first occurrence of any of the following Clinical Event Committee (CEC) confirmed adjudicated components of the primary composite endpoint: CV death (including fatal stroke and fatal myocardial infarction (MI)), non-fatal MI (excluding silent MI), or nonfatal stroke is presented.The first key secondary endpoint was time to first occurrence of any of the following adjudicated components of the composite endpoint: CV death (including fatal stroke and fatal MI), non-fatal stroke, non-fatal MI (excluding silent MI), or hospitalisation for unstable angina pectoris.The second key secondary endpoint was a composite endpoint of treatment sustainability, defined as the percentage of patients taking trial medication at trial end, maintained glycaemic control (HbA1c ≤7.0%) without need for rescue medication, without >2% weight gain, and without moderate/severe hypoglycaemic episodes during maintenance phase.The third key secondary endpoint was a composite endpoint of treatment sustainability, defined as percentage of patients who were on trial medication at trial end, maintained glycaemic control (HbA1c ≤7.0%) without need for rescue medication, and without >2% weight gain during maintenance phase.Percentage of participants occurrence of at least one of the following adjudicated components of CV death (including fatal stroke and fatal MI), non-fatal MI (excluding silent MI) and non-fatal stroke is presented as secondary CV endpoint.Percentage of participants occurrence of at least one of the following adjudicated components of CV death (including fatal stroke and fatal MI), non-fatal MI (excluding silent MI), non-fatal stroke, and hospitalisation for unstable angina pectoris is presented as secondary CV endpoint.Change from baseline to final visit in HbA1c is presented as secondary diabetes-related endpoint.
Thus this endpoint was not analysed and only the baseline data collected were analysed and the results are reported in this CGM substudy endpoint.Baseline data for the continuous glucose monitoring sub-study was collected and analyzed. Результаты встреч.
Data for last value on treatment (LVOT) to baseline (base) is presented.The endpoint change from baseline of ISR at fixed glucose concentration at 208 weeks as derived from a 3-hour meal tolerance test is Beta-cell function sub-study endpoint.Occurrence of accelerated cognitive decline based on regression based index (RBI) score at end of follow-up (a dichotomous outcome measure; presence or absence of accelerated cognitive decline) is Cognition sub-study endpoint.Baseline data for the continuous glucose monitoring sub-study was collected and analyzed. However, the participant number was far less than original planned.
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